- A Cross-sectional Study on the Risk Factors Related to Fatty Liver.
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S H Ohm, B C Yoo, S J Kim, C U Lee, K T Pai, S C Kim, H R Shin
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Korean J Prev Med. 1993;26(2):179-191.
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- Generally fatty liver is attributed either to chronic alcoholism, diabetes mellitus, or obesity. Based upon this commonly held clinical brief, this study was conducted to investigate the contributing factors of fatty liver and odds ratio (OR) of known contributing factors. A sample of 310 male participants, who visited at Seoul Paik Automated Multiphasic Health Testing System from November 1991 to December 1991, was separated into 112 cases and 198 controls by ultrasonographic finding. There were statistically significant difference between fatty liver and normal in triglyceride(TG), body mass index(BMI), alanine aminotransferase(ALT), high density lipoprotein cholesterol (HDL-C), fasting blood sugar (FBS), alcohol consumption, low density lipoprotein cholesterol (LDL-C), total cholesterol, gamma-glutamyl transferase (gamma-GT), duration of alcohol intake and alkaline phospahtase (Alk.P)(P<0.01, P<0.05). The statistically significant elevated odds ratio were noted for TG (4.48, confidence interval (CI) 2.66-7.55, P=0.000), alcohol consumption(3.24, CI 1.56-6.23, P=0.002), BMI(3.05, CI 1.87-4.97, P=0.000), and FBS(2.59, CI 1.53-4.40, P=0.000). In summary, it is suggested that the fatty liver could be preventive by avoiding such deleterious factors as high fat diet, alcohol and obesity.
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Summary
- The Type of Anemia in Organic Solvent Workers by MCV and RDW.
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S J Kim, S H Ohm, D H Kim, C U Lee, J H Chun, S C Kim, K T Pae
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Korean J Prev Med. 1992;25(2):162-171.
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- The hematologic effect by low-concentration and repeated exposure to mixed organic solvent remains obscure. This study was performed to evaluate the hematologic effect by mixed organic solvent exposure, especially on the type of anemia by mean corpuscular volume(MCV) and red blood cell distribution width(RDW). The subject were 64 organic solvent workers(male 4, female 60) and 78 general workers(male 18, female 60) who showed anemic tendency in worker's health examination which carried out by Pusan Paik Hospital from January to December, 1988. The author gained some hematologic findings (hemoglobin, hematocrit, RBC, WBC, MCV, MCHC, platelet count, ESR, RDW) from auto-analysis method by coulter counter S plus IV, and compared the type of anemia by MCV and RDW. In the pilot study for estimating the prevalence of anemia according to the type of job, the prevalence rate was higher in organic solvent workers than in public officials as 10.9% and 4.1% respectively. There were statistical significance in the value of hemoglobin, hematocrit, MCV, MCHC, platelet count, ESR, RDW between the two study groups with more severe anemic tendency in organic solvent workers. The type of anemia in organic solvent workers was microcytic and anisocytic with the mean value of 68.28+/-8.3fL of MCV and 19.1+/-4.0% of RDW.
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Summary
- Chest Radiological Changes after Cessation and Decrease of Exposure to Welding Fume in Shipyard Welders.
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H S Sohn, J T Lee, H R Shin, C U Lee, K T Pae, H J Park, Y W Kim
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Korean J Prev Med. 1989;22(3):328-336.
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- 27 shipyard welders were diagnosed as pneumoconiosis and suspected pneumoconiosis(1976 - 1988) by chest radiographs and were observed over three years. 27 welders were divided into three groups by the state of exposure to welding fume i.e. cessation, decrease or continuity of exposure. And we observed the changing pattern of the chest radiographs of 27 welders with the passage of time. The results were as follows; 1. Group I (ceased exposure to welding fume) were 10 cases: suspected pneumoconiosis, 7 cases: pneumoconiosis). Chest radiographs of all cases were improved. The shape and size of small opacities was improved in 6 cases(85.7%) and did not changed in 1 case(14.3%) out of 7 pneumoconiosis welders. 2. Group II (decreased exposure to welding fume) were 5 cases(2 cases: suspected pneumoconiosis, 3 cases: pneumoconiosis). Chest radiographs were progressed in 2 cases(40%), did not changed in 1 case(20%), were improved in 2 cases(40%) out of 5 cases. The shaped and size of small opacities was progressed in 1 case(33.3%) and was improved in 2 cases(66.7%) out of 3 pneumoconiosis welders. 3. Group III (continued exposure to welding fume) were 12 cases(1 case: suspected pneumoconiosis, 11 cases: pneumoconiosis). Chest radiographs were progressed in 9 cases(75%), did not changed in 3 cases(25%) out of 12 cases. The shape and size opacities was progressed in 1 case(9.1%) and did not changed in 10 cases(90.9%) out of 11 pneumoconiosis welders. 4. The average duration for development into suspected pneumoconiosis was 6.6 years and for progression of each one category after that was 2.2 years(p<0.01). The radiological appearance of pneumoconiosis had disappeared or decreased after cessation of exposure to the welding fume. So that, early detection and control e.g., change of department of pneumoconiosis of welders by screening program will be important for medical surveillance of welders.
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Summary
- The Epidemiologial Study on the Welders' Pneumoconiosis among Shipyard Welders in Pusan Area.
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C U Lee, G Y Cho, S C Kim, K T Pae, Y W Kim, I G Yun
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Korean J Prev Med. 1989;22(1):153-161.
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- Authors studied on the prevalence of 94 cases of pneumoconiosis who were found out through the screening test on 1,062 workers engaged in welding process at 36 shipyard in Pusan area from March 1st, 1986 to November 30th, 1986. The result were as follows; 1. Dust concentration was measured 4.49+/-0.54 mg/m3 in the small scale shipyard while it was 6.25+/-1.08 mg/m3 in the large one. 2. The prevalence of welder's lung was 8.9% (male:8.5%, female:12.0%) and this is consist of 4.9% suspected pneumoconiosis and 4.0% pneumoconiosis more than category 1/0. 3. The prevalence was significantly increased according to the duration of dust exposure (p<0.05), and it showed the increasing tendency by the age group. 4. The prevalence was significantly higher in the large scale shipyard than is the small scale one(p<0.01). 5. The type and shape of opacities were 71.4% of p type and 28.6% of q type, however no pneumoconiosis with r type observed in this study. 6. The main subjective symptoms were the sputum(29.8%), coughing(25.5%), shortness of breath(20.2%), fatigue(6.4%), and chest pain(5.3%). In other hand, 57.4% of pneumoconiosis were asymptomatic. 7. The prevalence of pulmonary tuberculosis was radiologically 1.7% in all subjects including 5.3% in pneumoconiosis and 1.3% in no pneumoconiosis(p<0.01).
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Summary
- A study on the properities of the paralytic shellfish poison.
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J T Lee, H S Shon, D H Moon, C U Lee, S C Kim, K T Pae, J Y Kim, Y W Kim, N W Paik
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Korean J Prev Med. 1988;21(1):163-171.
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- The paralytic shellfish poisoning was occurred among 25 laborers who worked at breaking-up of ships in Pusan for 5 days from March 29 to April 2 of 1986. For the purpose of accurately defining the paralytic shellfish poison(PSP), the authors carried out mouse bioassay and chemical analysis. The results were summarized as follows: 1. The mean amount of paralytic shellfish toxin was 1,207.8 microgram per 100gm meat, and the mean death time of mouse was 5 minutes 16 second. 2. The properties of the PSP were mainly gonyautoxin group by chemical analysis(TLC, IR, 1H-NMR).
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Summary
- A Study on the Status of Working Environment of Some Rubber and Chemical Products Manufacturing Industries in Busan.
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J Y Kim, C U Lee, K T Pea, J H Kim, J O Kim, D K Kim, Y W Kim
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Korean J Prev Med. 1981;14(1):97-110.
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- This study was conducted in order to investigate the status of harmful working environment on twelve rubber and ten chemical products manufacturing industries in Busan area over a period of five months from June 1 to October 31, 1980. The summarized results were as follows; 1. The highest and lowest mean values of harmful environmental elements in workroom of rubber products manufacturing industries were noted in twisting (98.7dB) and coating department (77.3dB) to noise, molding (6.43mg/m3) and forming (1.33mg/m3) to dust, bonding (toluene 463.7ppm, xylene 83.3ppm and benzene 6.7ppm, respectively) to organic solvents respectively. Also in chemical products manufacturing, they were noted in grinding (95.1dB) and shining department (76.8dB) to noise, packing (4.30mg/m3) and staining (3.20mg/m3) to dust, shining (393.3ppm and 375.0ppm, respectively) and varnishing(125.5ppm and 121.7ppm, respectively) to toluene and xylene, and scattering (51.8ppm) and mixing (23.9ppm) to benzene, respectively. 2. The mean values of harmful elements in workroom of rubber products manufacturing were 86.3dB to noise, 4.16mg/m3 to dust, 258.2ppm to toluene, 230.3ppm to xylene, and 54.0ppm to benzene, respectively. Also in chemical products manufacturing, they were 85.2dB to noise, 3.69mg/m3 to dust, 227.9ppm to toluene, 213.2 ppm to xylene, and 36.3ppm to benzene, respectively. 3. Number of workers exposed to harmful working environment, over TLV, of a total 10,195 workers in rubber manufacturing were 1,002(9.8%) to noise, 212(2.1%) to dust, 1,581(15.5%) to tolune, 1,509(14.8%) to xylene, and 1,524(15.0%) to benzene, respectively. Number of workers exposed to harmful working environment, over TLV, of a 1,913 workers in chemical products manufacturing were 112(5.9%) to noise, 132(6.9%) to each organic solvent, respectively. 4. The values of noise and dust of rubber and chemical products manufacturing in 1980 were lower then those in 1977, but the value of organic solvent in 1980 was with that in 1977.
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KSPM
